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KMID : 0829220210450040139
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Korean Journal of Oral and Maxillofacial Pathology
2021 Volume.45 No. 4 p.139 ~ p.144
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Non-Keratinizing Squamous Cell Carcinoma from the Nasal Cavity Mimicking Palatal Salivary Gland Tumor: Case Report
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Lee Hwan-Gyu
Han Da-Wool
Kim Hyoun-Min
Kim Dong-Wook
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Abstract
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Non-keratinizing squamous cell carcinoma (NKSCC) is a rare malignancy of the nose and paranasal sinuses which is characterized by a unique anastomosing ribbon-like growth pattern with absent of limited maturation and keratinization. NKSCC accounts for 10-27% of sinonasal squamous cell carcinomas and some of the NKSCCs are reported to be associated with high risk-HPV infection. Advanced lesion can involve the oral cavity with oral symptoms of palatal bulging, surface ulceration mimicking salivary gland tumors. Herein, we report a case of NKSCC of a 46-year old male, which clinically presented as a bulging mass on the mid palate and mimicked a palatal salivary gland tumor. We reviewed the clinical and histopathological considerations required for differential diagnosis of sinonasal carcinoma involving the oral cavity.
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KEYWORD
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Non-keratinizing squamous cell carcinoma, Sinonasal carcinoma, Human papillomavirus, p16, Mucoepidermoid carcinoma
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